First Draft Genome Sequence of the Dourine Causative Agent: Trypanosoma Equiperdum Strain OVI

Efficacy of Some Trypanocidal Drug Against Trypanosoma equiperdum OVI in Experimentally Infected Mice in Debre Zeit, Ethiopia

Trypanocidal drugs remain the principal method of animal Trypanosomiasis control in most African counties. However, there is growing concern that future effectiveness may be severely curtailed by wide spread drug resistance. This study was therefore, conducted to assess the efficacy of diminazene diaceturate and cymelarsan against Trypanosoma equiperdum OVI South Africa strain in experimentally...

An investigation of dourine and isolation of Trypanosoma equiperdum in Iran

Genome-Wide SNP Analysis Reveals Distinct Origins of Trypanosoma evansi and Trypanosoma equiperdum

Trypanosomes cause a variety of diseases in man and domestic animals in Africa, Latin America, and Asia. In the Trypanozoon subgenus, Trypanosoma brucei gambiense and Trypanosoma brucei rhodesiense cause human African trypanosomiasis, whereas Trypanosoma brucei brucei, Trypanosoma evansi, and Trypanosoma equiperdum are responsible for nagana, surra, and dourine in domestic animals, respectively...

Trypanosoma equiperdum Low Molecular Weight Proteins As Candidates for Specific Serological Diagnosis of Dourine

The diagnosis of dourine can be difficult because the clinical signs of this disease in horses are similar to those of surra, caused by Trypanosoma evansi. Moreover, T. equiperdum and T. evansi are closely related and, so far, they cannot be distinguished using serological tests. In a previous work, the T. equiperdum protein pattern recognized by antibodies from dourine-infected horses and the ...

The establishment of in vitro culture and drug screening systems for a newly isolated strain of Trypanosoma equiperdum

Dourine is caused by Trypanosoma equiperdum via coitus with an infected horse. Although dourine is distributed in Equidae worldwide and is listed as an internationally important animal disease by the World Organization for Animal Health (OIE), no effective treatment strategies have been established. In addition, there are no reports on drug discovery, because no drug screening system exists for...